The power
of truth
SimVis Gekko™’s unique technology has been licenced by 2EyesVision and is based on 10+ years of research and continued development at VioBio Lab (CSIC), a worldwide recognised leading research group in visual optics.

Our references

4 patents, 9 grants and awards, 18 papers, 23+ press appearances, 6 clinical sessions, 25 seminars and conferences

Scientific Publications
2013
1. de Gracia P, Dorronsoro C, Sanchez-Gonzalez A, Sawides L, Marcos S. Experimental simulation of simultaneous vision. Invest Ophthalmol Vis Sci 2013 Jan 17;54(1):415-422. For more information, click here.
2016
2. Dorronsoro C, Radhakrishnan A, de Gracia P, Sawides L, Marcos S. Perceived image quality with simulated segmented bifocal corrections. Biomed Opt Express. 2016 Nov 1; 7(11): 4388–4399. Published online 2016 Oct 3. doi: 10.1364/BOE.7.004388. For more information, click here.
3. Dorronsoro C, Radhakrishnan A, Alonso-Sanz J, Pascual D, Velasco-Ocana M, Perez-Merino P, and Marcos S. Portable simultaneous vision device to simulate multifocal corrections. Optica 3, 918-924 (2016). For more information, click here.
2017
4. Akondi V, Dorronsoro C, Gambra E, Marcos S. Temporal multiplexing to simulate multifocal intraocular lenses: theoretical considerations. Biomed Opt Express 2017 Jun 23;8(7):3410-3425. For more information, click here.
5. Vinas M, Dorronsoro C, Radhakrishnan A, Benedi-Garcia C, LaVilla EA, Schwiegerling J, et al. Comparison of vision through surface modulated and spatial light modulated multifocal optics. Biomed Opt Express 2017 Mar 3;8(4):2055-2068. For more information, click here.
6. Vinas M, Dorronsoro C, Gonzalez V, Cortes D, Radhakrishnan A, Marcos S. Testing vision with angular and radial multifocal designs using Adaptive Optics. Vision Res 2017 Mar;132:85-96. For more information, click here.
2018
7. Akondi V, Sawides L, Marrakchi Y, Gambra E, Marcos S, and Dorronsoro C. Experimental validations of a tunable-lens-based visual demonstrator of multifocal corrections. Biomed. Opt. Express 9, 6302-6317 (2018), click here.
2019
8. Vinas M, Benedi C, Sissati C, Pascual D, Vias A, Dorronsoro C, et al. Visual Simulators replicate vision with multifocal lenses. Sci Rep 2019 For more information, click here.
9. Dorronsoro C, Barcala X, Gambra E, Akondi V, Sawides L, Marrakchi Y, et al. Tunable lenses: dynamic characterization and fine-tuned control for high-speed applications. Opt Express 2019 Feb 4;27(3):2085-2100 For more information, click here.
10. Radhakrishnan A, Pascual D, Marcos S, Dorronsoro C. Vision with different presbyopia corrections simulated with a portable binocular visual simulator. PLoS ONE 14(8): e0221144 For more information, click here.
11. Vinas M, Aissati S, Romero M, Benedi-Garcia C, Garzon N, Poyales F, Dorronsoro C, Marcos S. Pre-operative simulation of post-operative multifocal vision. Biomed. Opt. Express 10, 5801-5817 (2019) For more information, click here.
2020
12. Marcos S, Benedí‐García C, Aissati S, Gonzalez‐Ramos AM, Lago CM, Radhkrishnan A, Romero M, Vedhakrishnan S, Sawides L & Vinas M. VioBio lab adaptive optics: technology and applications by women vision scientists. Ophthalmic Physiol Opt 2020; 40: 75– 87. For more information, click here.
13. Vinas M, Aissati S, Gonzalez-Ramos A, Romero M, Sawides L, Akondi V, Gambra E, Dorronsoro C, Karkkainen T, Nankivil D, Marcos M; Optical and Visual Quality With Physical and Visually Simulated Presbyopic Multifocal Contact Lenses. Trans. Vis. Sci. Tech. 2020;9(10):20. For more information, click here.
2021
14. Barcala, X., Vinas, M., Romero, M. et al.; Multifocal acceptance score to evaluate vision: MAS-2EV. Sci Rep 11, 1397 (2021). For more information, click here.
15. Marcos, S., Martinez-Enriquez, E., Vinas, M., de Castro, A., Dorronsoro, C., Pil Bang, S., Yoon, G., Artal, P.; Simulating Outcomes of Cataract Surgery: Important Advances in Ophthalmology. Annual Review of Biomedical Engineering 2021 23:1, 277-306. For more information, click here.
16. Benedi-Garcia, C., Vinas, M., Lago, C. M., Aissati S., De Castro, A., Dorronsoro, C, and Marcos, S.; Optical and visual quality of real intraocular lenses physically projected on the patient’s eye. Biomed. Opt. Express 12, 6360-6374 (2021). For more information, click here.
17. Sawides, L., de Castro, A., Lago, C. M., Barcala, X., Zaytouny, A., Marcos, S., & Dorronsoro, C.; SimVis simulations of multifocal IOL designs based on public-literature data. Optical Design and Engineering VIII (Vol. 11871, pp. 122-132). SPIE. (2021 Sept.). For more information, click here.
18. Barcala, X., Gambra, E., Sawides, L., Martinez-Ibarburu, I., Rofriguez-Lopez, V., & Dorronsoro, C. ; Optical quality evaluation for active afocal systems. Optical Design and Engineering VIII (Vol. 11871, pp. 133-143). SPIE.(2021 Sept.). For more information, click here.
2022
19. Barcala, X., Vinas, M., Ruiz, S., Hidalgo, F., Nankivil, D., Karkkainen, T., Gambra, E., Dorronsoro, D., & Marcos, S.; Multifocal contact lens vision simulated with a clinical binocular simulator. Contact Lens and Anterior Eye 2022, 45(6):101716. For more information, click here.
20. Barcala, X., Zaytouny, A., Rego-Lorca, D., Sanchez-Quiros, J., Sanchez-Jean, R., Martinez-de-la-Casa, J. M., Dorronsoro, C., & Marcos, S.; Visual simulations of presbyopic corrections through cataract opacification. Journal of Cataract & Refractive Surgery 2022, 10: 1097. For more information, click here.
21. Lopez-de-Haro, A. G., Barcala, X., Martinez-Ibarburu, I., Marrakchi, Y., Gambra, E., Rodriguez-Lopez, V., Sawides, L., & Dorronsoro, C.; Closed-loop experimental optimization of tunable lenses. Applied Optics 2022, 61(27), 8091-8099. For more information, click here.
22. Lago, C. M., de Castro, A., Benedí-García, C., Aissati, S., & Marcos, S. (2022).; Evaluating the effect of ocular aberrations on the simulated performance of a new refractive IOL design using adaptive optics. Biomedical Optics Express 2022, 13(12), 6682-6694. For more information, click here.
2023
23. Marrakchi, Y., Barcala, X., Gambra, E., Aissati, S., Martinez-Ibarburu, I., Dorronsoro C. & Sawides, L.; Experimental characterization, modelling and compensation of temperature effects in optotunable lenses. Sci Rep 13, 1575 (2023). For more information, click here.
24. Rodriguez-Lopez, V.; Barcala, X.; Zaytouny, A.; Dorronsoro, C.; Peli, E.; Marcos, S. (2023); Monovision Correction Preference and Eye Dominance Measurements. Trans. Vis. Sci. Tech. 2023;12(3):18.doi:https://doi.org/10.1167/tvst.12.3.18. For more information, click here.

LICENSED PATENTS
SimVis+ technology is protected by three patents that 2EYES VISION has licensed. The patents protect (1) the general concept of pure simultaneous vision simulation by an optical device (Patent #1); (2) the concept and realization of a simultaneous vision system based on temporary multiplexing with an opto-adjustable lens (Patent #2), which makes the system very compact, robust and simple; (3) the incorporation of masks for spatial segmentation in an optical system of simultaneous vision (Patent #3), which introduces the possibility of simulating designs with spatial distribution.
2009
1. P200930055, with title “Instrument for the simulation of multifocal ophthalmic corrections”, filed on the 8th of April, 2009 at the Spanish Patent and Trade Mark Office, and currently extended to Europe and USA.
2013
2. P201331436, with title “Miniaturized simultaneous vision simulator instrument”, filed on the 1st of October, 2013 at the Spanish Patent and Trade Mark Office, and currently extended to USA, Europe and India.
2015
3. P201531397, with title “Miniaturized simultaneous vision simulator instrument by mask generation”, filed on the 30th of September, 2015 at the Spanish Patent and Trade Mark Office and currently extended to USA, Europe and India.
After close collaboration between VioBio Lab (CSIC) and 2EYES VISION, we have filled in a new patent with shared titularity (CSIC -66%- and 2EYES VISION -34%-). This patent protects an optical autocalibration focimeter that, in addition to increasing the degree of protection of the patents mentioned above, establishes the technological basis of the calibrating cradle (Patent #3).
2017
4. P201730854, with title “Device for determining the optical power of lenses and measurement method”, filed on the 28th of June, 2017 at the Spanish Patent and Trade Mark Office and currently PCT extended with registration number PCT/ES2018/070464.

GRANTS AND AWARDS
Different institutions have shown their interest in the project and granted more than 700.000 € in funding, among these, we can find:
2016
1. Ministry of Economy and Competition:
- Doctorados Industriales: covers 64% of the salary of a PhD candidate 4 years.
- Torres Quevedo: covers 70% of the salary of an R&D doctor 3 years.
2. EIt health Accelerator.
2017
3. EIt health Accelerator.
4. Madrid+d Awards. Award for the best 2017 patent “'Miniaturized simultaneous vision simulator instrument.”
5. SME Innovation associated.
2018
6. Centre for the Development of Industrial Technology (CDTI)-NEOTEC.
7. Autonomous Community of Madrid. Doctorados Industriales: covers 64% of the salary of a PhD candidate 4 years.
2019
8. Autonomous Community of Madrid. Doctorados Industriales: covers 64% of the salary of a PhD candidate 4 years.
9. South Summit Spain Startup 2019. Winner of the Healthcare and Biotech track of the Spain Startup – South Summit

SEMINARS AND CONFERENCES
Participation in conferences and international congresses.
2014
1. S. Marcos "Testing vision with multifocal lenses using a simultaneous vision device", International Presbyopia Conference, London, UK 2014.
2015
2. S. Marcos, "Simulating multifocality with a portable simultaneous vision instrument" XXIII Congress of the European Society of Cataract and Refractive Surgery, Barcelona, España (2015).
2016
3. S. Marcos, “Handheld device for simulating multifocal lens outcomes”, XXIV Congress of the European Society of Cataract and Refractive Surgery, Copenhagen, Dinamarca (2016).
4. C. Dorronsoro, A, Radhakrishnan, JR Alonso-Sanz, D. Pascual, E. Gambra, V. Akondi, S. Marcos, “SimVis: see-thru simulation of presbyopic corrections”, Frontiers in Optics, Optical Society of America, Rochester, NY (2016).
5. S. Aissati, M. Vinas. C. Dorronsoro, S. Marcos, Simulation of multifocal corrections using a tunable-based simultaneous vision simulator in an Adaptive Optics system environment. IONS Naples, Optical Society of America, Napoles, Italia (2016). Poster.
6. Maria Vinas, Carlos Dorronsoro, Aiswaryah Radhakrishnan, Edward Anthony LaVilla, Jim Schwiegerling, Susana Marcos. Testing vision with physical and simulated multifocal corrections in an adaptive optics visual simulator, Association for Research in Vision and Ophthalmology, Seattle, WA, USA (2016) For more information, click here.
7. V. Akondi, C. Dorronsoro, E. Gambra, M. Vinas, D. Pascual, S. Aissati, S. Marcos. Temporal multiplexing and simulation of multifocal intraocular lenses. Frontiers in Optics, Optical Society of America, Rochester, NY, USA (2016). Oral communication.
8. V. Akondi, C. Dorronsoro, S. Marcos. Simulation of multifocal lenses through a temporal multiplexing approach , Visual and Physiological Optics Meeting, Antwerp, Belgium (2016).
2017
9. S. Marcos "Wearable see-thru binocular simulator of multifocal and monovision presbyopic corrections", Wavefront Congress, San José, California, USA (2017).
10. C. Dorronsoro , JM Alonso-Sanz , D Pascual , A Radhakrishnan , M Velasco-OCana , P. Perez-Merino , S, Marcos, "Visión con correcciones de presbicia multifocales simuladas con un dispositivo miniaturizado de visión simultánea". XI National Optical Conference, Salamanca, Spain. Oral communication.
11. C. Dorronsoro; J.L. Méndez; E. Gambra; N. Alejandre; P. Pérez Merino; S. Marcos. MAS: The Multifocal Acceptance Score. Association for Research in Vision and Ophthalmology, Baltimore, USA (2017). Poster.
12. C. Dorronsoro; J.L. Méndez; E. Gambra; N. Alejandre; P. Pérez Merino; S. Marcos. MAS: The Multifocal Acceptance Score. Association for Research in Vision and Ophthalmology, Baltimore, USA (2017). Poster.
13. X. Barcala; E. Gambra; C. Dorronsoro; S. Marcos. Characterization of the dynamics response of tunable lenses with a high speed focimeter. The International OSA Network of Students (IONS), Paris, Francia (2017). Poster.
2018
14. S. Aissati; M. Viñas; M. Romero, J.L. Mendez González; C. Benedí; E. Gambra; V. Akondi; N. Garzón; F. Poyales; C. Dorronsoro; S. Marcos.Visual simulation of multifocal lenses in patients before and after implantation of diffractive trifocal lenses. XI Workshop on Adaptive Optics for Industry and Medicine, Murcia, España (2018). Oral communication.
15. M. Vinas; M. Romero; S. Aissati et al. Comparison of multifocal visual simulations in patients before and after implantation of diffractive trifocal lenses. Association for Research in Vision and Ophthalmology, Honolulu, Hawai, USA (2018). Poster.
16. F. Poyales; C. Dorronsoro; S. Marcos. Comparación de simuladores visuales multifocales antes y después del implante de lentes trifocales difractivas en pacientes. XII National Optical Conference, Castellón, Spain (2018). Oral Communication.
17. X. Barcala Gosende; M. Romero; M. Vinas; J.L. Mendez-Gonzalez; E. Gambra; C. Dorronsoro; S. Marcos. “Repeatability of the multifocal acceptance score (MAS)”. Free paper. ESCRS Viena 2018
18. X. Barcala; E. Gambra; S. Marcos; C. Dorronsoro. A high-speed focimeter to characterize the dynamic response of tunable lenses in the visual simulation of multifocal patterns. European Meeting on Visual and Physiological Optics, Athens, Greece (2018).
2019
19. Xoana Barcala, Mercedes Romero, Nuria Garzón, Francisco Poyales, Enrique Gambra, Susana Marcos, Carlos Dorronsoro. "Effect of cataract on pre-operative predictions of multifocal acceptance with SimVis Gekko". Free Paper. ESCRS Paris (2019)
20. Victor Rodriguez-Lopez, Xoana Barcala, Enrique Gambra, Lucie Sawides, Susana Marcos, Carlos Dorronsoro. "Can tunable lenses provide accurate multifocal simulations?" Poster. IONS Barcelona (2019).
21. Xoana Barcala, Ivan Martinez-Ibarburu, Victor Rodriguez-Lopez, Enrique Gambra, Carlos Dorronsoro. "Image quality of tunable-lens based visual simulators" Poster. IONS Barcelona (2019).
22. Dorronsoro, Carlos; Rodríguez Lopez, Victor; Barcala, Xoana; Gambra, Enrique; Akondi, Vyas; Sawides, Lucie; Marrakchi, Yassine; Lage, Eduardo; Geisler, Wilson S.; Marcos, Susana. "Perceptual and physical limits to temporal multiplexing simulation of multifocal corrections". Oral Communication. ARVO (2019)
23. Maria Vinas “Optical and visual quality with physical and visually simulated presbyopic multifocal contact lenses”. Paper Session. ARVO (2019)
24. Barcala, Xoana; Vinas, Maria; Gambra, Enrique; Marcos, Susana; Dorronsoro, Carlos."Perceptual differences across binocular corrections for presbyopia". Oral Communication. ARVO (2019)
2020
25. X. Barcala, M. Vinas, F. Hidalgo, S. Ruiz, D. Nankivil, T. Karkkainen, K. Chehab, C. Dorronsoro, S. Marcos. Comparison of vision with multifocal contact lenses and SimVis Gekko in a clinical site. Online ARVO 2020
Invitations to seminars in international centers
2015
1. “Exploring multifocal vision with a simultaneous vision simulator”, Schepens Eye Research Institute/ Mass Eye & Ear/Harvard Medical School, Boston, MA, USA (2015).
2018
2. "Having patients experience multifocal vision", Schepens Eye Research Institute/ Mass Eye & Ear/Harvard Medical School, Boston, MA, USA (2018).
Invitations to seminars in national centers (Spain)
2015
1. “New technologies to optimize the selection of IOLs”, Fernández Vega Ophtalmological Institute , Oviedo, Spain (2015).
2. “Exploring multifocal vision with a simultaneous vision simulator”, Schepens Eye Research Institute/ Mass Eye & Ear/Harvard Medical School, Boston, MA, USA (2015).